Jake Gyllenhaal and Anne Hathaway are in talks to star in Edward Zwick's upcoming "Love and Other Drugs" (previously titled "Pharma") for Fox 2000 and New Regency.

Based on the book "Hard Sell: The Evolution of a Viagra Salesman" by Jamie Reidy, the film follows a drug salesman who falls for a woman with Parkinson's (Hathaway).

Charles Randolph ("The Interpreter," "The Life of David Gale") wrote the screenplay. Filming, according to the Hollywood Reporter, is set to begin this fall.

Zwick most recently directed "Defiance." Hathaway, who recently starred in "Bride Wars," will soon be seen in "Alice in Wonderland." As for Gyllenhaal, he's got "Brothers," "Nailed" and "Prince of Persia: The Sands of Time" coming soon.

Gyllenhaal and Hathaway previously shared some onscreen time in Ang Lee's "Brokeback Mountain."