Harrison Ford and Brendan Fraser co-star in Tom Vaughan's upcoming drama "Extraordinary Measures," which was formerly titled "Crowley." You can now watch the first trailer right after the jump.

Based on the true story of John (Fraser) and Aileen Crowley (Keri Russell), the film follows a couple who finds a gifted researcher (Ford) with a potential cure for their two children's fatal genetic disorder.

Together they form a bio-tech company focused on developing a life-saving drug, but as it turns out, things don't exactly go according to plan, and soon, the two face a problem that tests their relationship.

To tell you the truth, I'm not quite sure what to think about this trailer at this stage. The cast sure looks awesome, but the preview sells the film as a saccharine melodrama, which can either be a hit or miss.

Still, it captured my attention enough to at least walk into this one with decent expectations. The title tough, is pretty lame. "Extraordinary Measures" opens Jan. 22, 2010.