John Erick Dowdle’s “Quarantine” topped the North American box office Friday with an estimated $5.3 million in ticket sales. It was an easy win for the horror remake, which debuted at 2,461 locations this weekend.

Following in second place was last weekend’s champion “Beverly Hills Chihuahua,” which took home another $4.5 million to reach a domestic total of $39.5 million after one week in release.

At No. 3, new entry “Body of Lies” collected $4.3 million. Directed by Ridley Scott, the film stars Russell Crowe and Leonardo DiCaprio as two CIA agents struggling to locate a terrorist.

The remaining wide releases of the weekend had troubles competing against existing box office players. “The Express” debuted in sixth place with $1.5 million, while Gil Kenan’s family adventure “City of Ember” only made it to No. 11 with a disappointing $950,000.

Still going strong was D.J. Caruso’s action thriller “Eagle Eye,” which ranked fourth with a Friday gross of $3.2 million. Following at No. 5 was “Nick and Norah’s Infinite Playlist” with $2.1 million.

Source: Box Office Mojo (www.boxofficemojo.com)